BDBM13061 4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile::4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile::CHEMBL1444::Letrozole

SMILES N#Cc1ccc(cc1)C(c1ccc(cc1)C#N)n1cncn1

InChI Key InChIKey=HPJKCIUCZWXJDR-UHFFFAOYSA-N

Data  2 KI  48 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13061   

TargetAromatase [1-48](Homo sapiens (Human))
BiomolÉCules Et Cibles Cellulaires Tumorales

LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)
Affinity DataIC50:  18nMAssay Description:The inhibitory activities of the compounds toward aromatase were determined in vitro using human placental microsomes and [1,2,6,7-3H]-androstenedion...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed